A correct diagnosis is essential in order to define the prognosis and to establish the most adequate therapeutic strategy with surgery, medical therapy and/or radiation therapy. Abdominal Sarcomas can cause generic symptoms, differently than Sarcomas of arms or legs, where a change of the anatomic aspect can lead to the diagnosis. Usual symptoms are: abdominal pain, early satiety, abdominal tension, intestinal sub-occlusion, and fatigue and. Also, depending on the size of the tumor, they can be detected during a clinical examination.

Sometimes the disease is completely asymptomatic and diagnosis is fortuitous. The main instrumental examinations are: Abdominal Ultrasound (Abdominal US), Computed Tomography (CT), and Nuclear Magnetic Resonance Imaging (NMRI). The Positron Emission Tomography (PET) it is normally used to detect metastasis. Biopsy can be performed during abdominal US and CT in order to achieve a cytological confirmation of the diagnosis.

Biopsy is of prime importance in patients undergoing upfront radiotherapy or chemotherapy, being the instrument to achieve a correct diagnosis and to choose the most appropriate treatment.

Anyway, every time health practitioner suspect a diagnosis of STS should address the patient to a specialized medical center that can offer an adequate diagnostic-therapeutic program.