The Bologna GIST STUDY GROUP is a multidisciplinary group which is composed of internists, oncologists, gastroenterologists, surgeons, radiologists, specialists in nuclear medicine, pathologists and molecular biologists. The physicians and healthcare professionals who make up the group have worked together for years and are experts in managing patients affected by GIST. The group offers the patient the possibility to use all the services necessary for diagnosis and treatment of his/her disease, such as the use of diagnostic exams among which are endoscopic ultrasound, CT, MRI, PET or molecular biology as well as the possibility to undergo surgery performed by surgeons expert in this pathology. There is also the possibility to use innovate medical treatment by taking part in international clinical trials. The patient is evaluated collectively by the group. Decisions made during the course of the meeting are then communicated to the patient who will be called for a visit at the Institute of “Hematology and Medical Oncology “L. e A. Seràgnoli. The diagnostic, therapeutic and follow-up program carried out by the group is periodically updated on the basis of the results of scientific literature and of national and international meetings. The group participates in clinical research programs thanks to the activation of international clinical testing that foresee the use of innovative drugs (see the Foreground or Research section). There are also pre-clinical trials aimed at the development of new drugs and useful methods to evaluate their efficacy.